Synthesis and structural studies of complexes of Cu, Co, Ni and Zn with isonicotinic acid hydrazide and isonicotinic acid (1-naphthylmethylene)hydrazide

Synthesis and structural studies of complexes of Cu, Co, Ni and Zn with isonicotinic acid hydrazide and isonicotinic acid (1-naphthylmethylene)hydrazide

Eight new complexes of Cu(II), Co(II), Ni(II) and Zn(II) with isonicotinic acid hydrazide (isoniazid, (INH)) and isonicotinic acid (1-naphthylmethylene)hydrazide (INNMH), having the formula of the type [M(INH)(ac)2] or [M(INNMH)(ac)2] (M = Co(II), Ni(II) and Zn(II)) and [Cu(INH)(ac)2]2, [Cu(INNMH)(ac)2]2, were synthesized and characterized. All complexes were characterized based on elemental an...

Isonicotinic Acid Hydrazide

Two nd-zn and sm-zn isonicotinic/nicotinic Acid complexes.

The 4f-3d heterometallic complexes [Nd(L)3(H2O)2]2(ZnCl4)3n • 4nH2O (1) (L = isonicotinic acid) and [Sm(L')3(H2O)2]2(ZnCl4)n • 2nH2O (2) (L' = nicotinic acid) have been obtained by hydrothermal reactions and structurally characterized by X-ray single-crystal diffractions. Both complexes feature an infinite 1-D polycationic chain-like structure. Photoluminescent investigations reveal that both c...

Synthesis, Characterization and Biological Studies of 2-(4-Nitrophenylaminocarbonyl)Benzoic Acid and Its Complexes with Cr(III), Co(II), Ni(II), Cu(II) and Zn(II)

Cr(III), Co(II), Ni(II), Cu(II) and Zn(II) salts of 2-(4-nitrophenylaminocarbonyl)benzoic acid were characterized by physical, analytical and spectroscopic studies and checked for their  in-vitro antimicrobial activity against three bacterial strains, Mycobacterium smegmatis (Gram +ve), Escherichia coli (Gram -ve), Pseudomonas aeuroginosa (Gram -ve) and three fung...

Synthesis and Biological Evaluation of Isonicotinic Acid Hydrazide Conjugated with Diethyelenetriaminepentaacetic Acid for Infection Imaging

Introduction: Isonicotinic acid hydrazide (INH) was coupled to diethylenetriaminepentaacetic acid (DTPA) via amide linkage. Primary object of the present invention was to propose a novel INH derivative based on DTPA, which form stable complexes with most of lanthanides and transition metals in periodic table. Another object of the present invention was to introduce a chelating group in INH with...